Background: Trastuzumab targets the human epidermal growth factor receptor 2 oncogene
and in combination with first-line therapy results in significantly improved survival outcomes …

Leptomeningeal metastasis (LM) in breast cancer is associated with significant morbidity
and mortality. While there is currently no standard therapy, treatment options include …

Abstract Objective/Background Progesterone-receptor negativity (PR−) is predictive of
adverse outcomes in estrogen receptor-positive (ER+) breast cancer. The Oncotype DX …

Background: Androgen receptor (AR) expression has emerged as a potential prognostic and
predictive marker in patients with triple negative breast cancer (TNBC). We conducted a …

Red cell exchange (RCE) is a common procedure in adults with sickle cell disease (SCD).
Implantable dual lumen Vortex (DLV) ports can be used for RCE in patients with poor …

Background: Local recurrence is a major concern in patients diagnosed with ductal
carcinoma in situ (DCIS). In invasive breast cancers, estrogen receptor (ER)(+)/progesterone …

Background Acute haemolytic transfusion reactions due to ABO incompatible blood
transfusion remain a leading cause of transfusion-associated morbidity and mortality in the …

Background Lepidic adenocarcinoma represents a histologic pattern of non-small cell lung
cancer that characteristically arises in the lung periphery with tracking alongside pre-existing …

Aims Neoadjuvant chemotherapy (NAC) is frequently used for the treatment of breast
cancer. We sought to analyse the clinical, morphological and immunohistochemical features …

Background Estrogen receptor-positive/progesterone-receptor negative breast cancer
(ER+/PR-BC) is recognized as a distinct clinical entity that is associated with potentially …