Carcinoid heart disease (CHD) is a consequence of valvular fibrosis triggered by vasoactive
substances released from neuroendocrine tumours, classically in those with metastatic …

During treatment of acute type A aortic dissection there is potential for both pre-and intra-
operative malperfusion. There are a number of monitoring strategies that may allow for …

Objectives To safely expand and adapt the normal workings of a large critical care unit in
response to the COVID-19 pandemic. Methods In April 2020, UK health systems were …

OBJECTIVES Patients undergoing cardiac surgery require adequate myocardial protection.
Manipulating myocardial metabolism may improve the extent of myocardial protection …

Simple Summary A proportion of patients with neuroendocrine tumours develop carcinoid
syndrome and subsequent carcinoid heart disease (CHD). Valve replacement is indicated …

Neuroendocrine tumours (NETs) are rare but once metastasised, can lead to the release of
vasoactive substances into the systemic circulation, and the classical features of carcinoid …

Introduction Carcinoid heart disease (CHD) is a consequence of neuroendocrine tumors
releasing 5-hydroxytryptamine (5-HT) into the systemic circulation, affecting right heart …

A 25-year-old woman with acute intermittent porphyria (AIP) was admitted to critical care
with exacerbation of her porphyria, poor pain control and subsequent respiratory failure …

On the occasions, when a patient is particularly unwell or unstable, clinical assessment and
routine non-invasive monitoring may be insufficient and more advanced techniques are …

Methods: A Retrospective study of 17 patients with CHD who had undergone heart-valve
replacement surgery between 2010 and 2019, from the Queen Elizabeth Hospital …