Storage conditions, sample integrity, interferences, and a decision tool for investigating unusual high-sensitivity cardiac troponin results

MA Lafrenière, V Tandon, C Ainsworth, K Nouri… - Clinical …, 2023 - Elsevier
The current definition of high-sensitivity cardiac troponin (hs-cTn) assays is laboratory-based
and their analytical attributes and characteristics have drawn significant attention in the …

Using the clinical chemistry score in the emergency department to detect adverse cardiac events: a diagnostic accuracy study

PA Kavsak, JO Cerasuolo, DT Ko, J Ma… - … Open Access Journal, 2020 - cmajopen.ca
Background: The ability to rule out or in a major adverse cardiac event (MACE) in patients
with suspected acute coronary syndrome at emergency department (ED) presentation would …

[HTML][HTML] Diagnostic performance of serial high-sensitivity cardiac troponin measurements in the emergency setting

PA Kavsak, MK Hewitt, SE Mondoux… - Journal of …, 2021 - mdpi.com
Serial high-sensitivity cardiac troponin (hsTn) testing in the emergency department (ED) and
the intensive cardiac care unit may assist physicians in ruling out or ruling in acute …

[HTML][HTML] Disagreement between cardiac troponin tests yielding a higher incidence of myocardial injury in the emergency setting

PA Kavsak, SE Mondoux, J Martin, MK Hewitt… - Journal of …, 2021 - mdpi.com
Differences in patient classification of myocardial injury between high-sensitivity cardiac
troponin (hs-cTn) assays have largely been attributed to assay design and analytical …

Clinical evaluation of Ortho Clinical Diagnostics high-sensitivity cardiac Troponin I assay in patients with symptoms suggestive of acute coronary syndrome

PA Kavsak, SE Mondoux, J Sherbino, J Ma… - Clinical …, 2020 - Elsevier
Background As more companies obtain regulatory approval for high-sensitivity cardiac
troponin (hs-cTn) assays there is an urgent need for independent analytical and clinical …

[HTML][HTML] Comparison of two biomarker only algorithms for early risk stratification in patients with suspected acute coronary syndrome

PA Kavsak, SE Mondoux, J Ma, J Sherbino… - International journal of …, 2020 - Elsevier
Background We developed a biomarker algorithm encompassing the clinical chemistry
score (CCS; which includes the combination of a random glucose concentration, an …

How do emergency departments and emergency leaders catalyze positive change through quality improvement collaborations?

LB Chartier, SE Mondoux, AS Stang… - Canadian Journal of …, 2019 - cambridge.org
ObjectivesQuality Improvement and Patient Safety (QIPS) plays an important role in
addressing shortcomings in optimal healthcare delivery. However, there is little published …

The COVID‐19 impact and characterization on substance use‐related emergency department visits for adolescents and young adults in Canada: Practical …

S Kim, N Rajack, SE Mondoux… - Journal of evaluation …, 2023 - Wiley Online Library
Abstract Rationale Coronavirus (COVID‐19)‐related stressors precipitated the mental health
crisis and increased substance use in Canada and worldwide. As the pandemic continues to …

Identifying very-low-risk patients for future myocardial infarction or death

PA Kavsak, JO Cerasuolo, MK Hewitt… - The Canadian …, 2023 - pubmed.ncbi.nlm.nih.gov
Identifying Very-Low-Risk Patients for Future Myocardial Infarction or Death Identifying Very-Low-Risk
Patients for Future Myocardial Infarction or Death Can J Cardiol. 2023 Apr;39(4):527-530. doi …

[HTML][HTML] High-sensitivity cardiac troponin i vs a clinical chemistry score for predicting all-cause mortality in an emergency department population

PA Kavsak, JO Cerasuolo, DT Ko, J Ma, J Sherbino… - CJC open, 2020 - Elsevier
Background For patients investigated for suspected acute coronary syndrome, there is
uncertainty if a single measurement of high-sensitivity cardiac troponin I (hs-cTnI) at …