Background: Diagnosis of neonatal early-onset sepsis is difficult because clinical signs and
laboratory tests are non-specific. Early antibiotic therapy is crucial for treatment success …

Antibiotic exposure at the beginning of life can lead to increased antimicrobial resistance
and perturbations of the developing microbiome. Early-life microbiome disruption increases …

Background Up to 7% of term and late-preterm neonates in high-income countries receive
antibiotics during the first 3 days of life because of suspected early-onset sepsis. The …

Background Neonatal early-onset sepsis (EOS) is one of the main causes of global neonatal
mortality and morbidity, and initiation of early antibiotic treatment is key. However, antibiotics …

Importance Appropriate use of antibiotics is life-saving in neonatal early-onset sepsis (EOS),
but overuse of antibiotics is associated with antimicrobial resistance and long-term adverse …

Background & aims In preterm infants, natural variation of breast milk composition makes it
difficult to achieve recommended macronutrient intakes with standard fortification. Evidence …

Objective To compare mortality and neurodevelopmental outcomes of outborn and inborn
preterm infants born at< 29 weeks of gestation admitted to Canadian neonatal intensive care …

Objective The aim of the article is to review the effectiveness of neonatal noninvasive high-
frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. Study …

Background: Uncertainty about the presence of infection results in unnecessary and
prolonged empiric antibiotic treatment of newborns at risk for early-onset sepsis (EOS). This …

Objective To assess the impact of variations in the definition of severe neurodevelopmental
impairment (NDI) on the incidence of severe NDI and the association with risk factors using …