PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function
T Tsunemi, TD Ashe, BE Morrison… - Science translational …, 2012 - science.org
Huntington's disease (HD) is caused by CAG repeat expansions in the (huntingtin htt) gene,
yielding proteins containing polyglutamine repeats that become misfolded and resist …
yielding proteins containing polyglutamine repeats that become misfolded and resist …
Excellent accuracy of glucose level in cystic fluid for diagnosis of pancreatic mucinous cysts
Background CEA in pancreatic cystic fluid (PCF) is standard for mucinous cysts diagnosis.
Glucose is an alternative, but its accuracy remains poorly described. Aims To evaluate PCF …
Glucose is an alternative, but its accuracy remains poorly described. Aims To evaluate PCF …
Clinical Impact of KRAS and GNAS Analysis Added to CEA and Cytology in Pancreatic Cystic Fluid Obtained by EUS-FNA
S Faias, M Duarte, C Albuquerque, JP da Silva… - Digestive diseases and …, 2018 - Springer
Background Pancreatic cysts are common incidental findings with malignant potential,
raising diagnostic and treatment dilemmas. Aims To determine the added value of KRAS …
raising diagnostic and treatment dilemmas. Aims To determine the added value of KRAS …
[HTML][HTML] A novel culture method that sustains ERα signaling in human breast cancer tissue microstructures
Background Estrogen receptor α (ERα) signaling is a defining and driving event in most
breast cancers; ERα is detected in malignant epithelial cells of 75% of all breast cancers …
breast cancers; ERα is detected in malignant epithelial cells of 75% of all breast cancers …
Optimization of immunocytochemistry in cytology: comparison of two protocols for fixation and preservation on cytospin and smear preparations
C Pinheiro, R Roque, A Adriano, P Mendes… - …, 2015 - Wiley Online Library
Objective A new protocol for fixation and slide preservation was evaluated in order to
improve the quality of immunocytochemical reactions on cytology slides. Methods The …
improve the quality of immunocytochemical reactions on cytology slides. Methods The …
[HTML][HTML] Preanalytic errors in anatomic pathology: study of 10,574 cases from five Portuguese hospitals
R Roque, H Henrique, P Aguiar - Diagnosis, 2015 - degruyter.com
Background: Identification of errors in anatomic pathology is an important issue in medical
practice. The main objective of this study was to determine the prevalence and characterize …
practice. The main objective of this study was to determine the prevalence and characterize …
Preservation of biomarkers immunoreactivity on cytospins protected with polyethylene glycol
I Srebotnik Kirbis, MJ Praça, RR Roque… - …, 2021 - Wiley Online Library
Introduction The aim of this retrospective study was to evaluate the preservation of
biomarkers immunoreactivity on cytospins protected with polyethylene glycol (PEG) …
biomarkers immunoreactivity on cytospins protected with polyethylene glycol (PEG) …
Establishment and characterization of a new patient-derived anaplastic thyroid cancer cell line (C3948), obtained through fine-needle aspiration cytology
Purpose Anaplastic thyroid cancer (ATC) is among the most aggressive and unresectable
tumors, presenting a bad prognosis. A better comprehension of the functional and molecular …
tumors, presenting a bad prognosis. A better comprehension of the functional and molecular …
Chromogranin A and NSE in cystic pancreatic neuroendocrine tumors
S Faias, S Prazeres, M Cunha… - … and research in …, 2021 - pubmed.ncbi.nlm.nih.gov
Chromogranin A and NSE in cystic pancreatic neuroendocrine tumors Chromogranin A and
NSE in cystic pancreatic neuroendocrine tumors Clin Res Hepatol Gastroenterol. 2021 Jul;45(4):101601 …
NSE in cystic pancreatic neuroendocrine tumors Clin Res Hepatol Gastroenterol. 2021 Jul;45(4):101601 …
Quality and performance indicators in Portuguese anatomical pathology laboratories: a panel validation by qualitative Delphi technique
Background In laboratory medicine, quality and performance indicators (QPIs) are essential
tools to ensure the quality of healthcare services and patient safety. QPIs allow comparison …
tools to ensure the quality of healthcare services and patient safety. QPIs allow comparison …