Objective To evaluate the relation between adherence to drug therapy, including placebo,
and mortality. Design Meta-analysis of observational studies. Data sources Electronic …

Atrial fibrillation (AF) is a growing public health problem associated with significant morbidity
and mortality. Numerous randomized controlled trials of warfarin have conclusively …

Hypertension Canada's 2020 guidelines for the prevention, diagnosis, risk assessment, and
treatment of hypertension in adults and children provide comprehensive, evidence-based …

Methods Our objective was to assess the validity and reliability of the Edmonton Frail Scale
(EFS) in a sample referred for CGA (Table 1). All patients aged 65+ years were approached …

Hypertension Canada provides annually updated, evidence-based guidelines for the
diagnosis, assessment, prevention, and treatment of hypertension in adults and children …

OBJECTIVE—Metformin is considered contraindicated in patients with heart failure because
of concerns over lactic acidosis, despite increasing evidence of potential benefit. The aim of …

Heart failure remains a common diagnosis, especially in older individuals. It continues to be
associated with significant morbidity and mortality, but major advances in both diagnosis …

Objective To review the literature on the association between antidiabetic agents and
morbidity and mortality in people with heart failure and diabetes. Design Systematic review …

Background Phosphate binders (calcium-based and calcium-free) are recommended to
lower serum phosphate and prevent hyperphosphataemia in patients with chronic kidney …

Hypertension Canada provides annually updated, evidence-based guidelines for the
diagnosis, assessment, prevention, and treatment of hypertension. This year, we introduce …