Iejimalide B, a marine macrolide, causes growth inhibition in a variety of cancer cell lines at
nanomolar concentrations. We have investigated the effects of Iejimalide B on cell cycle …

Vaccination, as an approach to prostate cancer, has largely focused on immunotherapy
utilizing specific molecules or allogeneic cells. Such methods are limited by the focused …

Previous studies comparing the effects of two histone deacetylase (HDAC) inhibitors,
trichostatin A (TSA) and CG-1521, have shown that these compounds selectively inhibit …

Methods We adopted a stress-first imaging protocol for all patients undergoing MPI at our
facility in which no pretest screening was performed and all patients were considered …

Publishing a paper in a medical journal is a common means of disseminating research
findings. The procedures for preparing and submitting a manuscript are largely consistent …

The use of speckle-tracking echocardiography (STE) is becoming an increasingly useful tool
in the evaluation of myocardial disease. STE software can track the motion of the specular …

Introduction: Current guidelines for myocardial perfusion imaging (MPI) encourage facilities
to adopt patient-centered risk mitigation strategies such as individualized radiotracer dosing …

Macrolide compounds have long been used as antibiotics, but recently some macrolides
have been proposed as cancer chemotherapeutics. Initial results from the NCI cancer cell …

The use of anti-androgen therapy for the treatment of invasive and metastatic prostate
cancer is common practice. However, after an initial response, the tumor frequently …

The anti‐androgen Casodex competes with the active metabolite of testosterone, 5α‐
dihydrotestosterone (5 α‐DHT), for binding to the androgen receptor (AR) and blocks normal …