The problems associated with pulmonary aspergilloma were assessed retrospectively in 23
patients presenting from 1953 to 1982. Haemoptysis occurred in over half the patients and in …

Pyrrolo [2, 3-d] pyrimidines containing a 5-(4-phenoxyphenyl) substituent are potent and
selective inhibitors of lck in vitro; some compounds are selective for lck over src. Data are …

We present the updated British Association for Sexual Health and HIV guidelines for HIV
post-exposure prophylaxis following sexual exposure (PEPSE). This document includes a …

In order to Investigate the contribution of histamine to bronchocon8trlctlon provoked by
Inhaled allergen and adenosine monophosph8te (AMP), we halveobserved the effects of …

In this study we investigated the effect of the selective and potent thromboxane A2 (TxA2)
receptor antagonist GR32191 on smooth muscle contraction induced by the TxA2 analogue …

A series of pyrrolo [2, 3-d] pyrimidines was synthesized and evaluated as inhibitors of Lck.
Lck accommodates a diverse set of substituents at N-7. Altering the substituent at N-7 …

Pyrrolo [2, 3-d] pyrimidines containing a 5-(4-phenoxyphenyl) substituent are novel, potent
and selective inhibitors of lck in vitro. Exploration of C-6 position of the pyrrolo [2, 3-d] …

A series of para-substituted 3-phenyl pyrazolopyrimidines was synthesized and evaluated
as inhibitors of lck. The nature of the substitution affected enzyme selectivity and potency for …

We present the updated British Association for Sexual Health and HIV (BASHH) guidelines
for post‐exposure prophylaxis (PEP) to HIV following sexual exposures, occupational …

A series of substituted thienopyridine ureas was prepared and evaluated for enzymatic and
cellular inhibition of KDR kinase activity. Several of these analogs, such as 2, are potent …