User profiles for "author:Nicolas Fernandez"

Nicolas F. Fernandez

Vizgen
Verified email at vizgen.com
Cited by 13326

[PDF][PDF] Immunology of COVID-19: current state of the science

N Vabret, GJ Britton, C Gruber, S Hegde, J Kim… - Immunity, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …

Varying conceptions of competence: an analysis of how health sciences educators define competence

N Fernandez, V Dory, LG Ste‐Marie… - Medical …, 2012 - Wiley Online Library
Medical Education 2012: 46: 357–365 Context Current debate in medical education focuses
on the nature of 'competency‐based medical education'(CBME) and whether or not it should …

[HTML][HTML] Cannabis and its secondary metabolites: their use as therapeutic drugs, toxicological aspects, and analytical determination

J Gonçalves, T Rosado, S Soares, AY Simão… - Medicines, 2019 - mdpi.com
Although the medicinal properties of Cannabis species have been known for centuries, the
interest on its main active secondary metabolites as therapeutic alternatives for several …

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

MV Kuleshov, MR Jones, AD Rouillard… - Nucleic acids …, 2016 - academic.oup.com
Enrichment analysis is a popular method for analyzing gene sets generated by genome-
wide experiments. Here we present a significant update to one of the tools in this domain …

[HTML][HTML] The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins

AD Rouillard, GW Gundersen, NF Fernandez… - Database, 2016 - academic.oup.com
Genomics, epigenomics, transcriptomics, proteomics and metabolomics efforts rapidly
generate a plethora of data on the activity and levels of biomolecules within mammalian …

Single-cell immune landscape of human atherosclerotic plaques

DM Fernandez, AH Rahman, NF Fernandez… - Nature medicine, 2019 - nature.com
Atherosclerosis is driven by multifaceted contributions of the immune system within the
circulation and at vascular focal sites. However, specific characteristics of dysregulated …

Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma

A Magen, P Hamon, N Fiaschi, BY Soong, MD Park… - Nature medicine, 2023 - nature.com
Despite no apparent defects in T cell priming and recruitment to tumors, a large subset of T
cell rich tumors fail to respond to immune checkpoint blockade (ICB). We leveraged a …

Differential cytokine contributions of perivascular haematopoietic stem cell niches

N Asada, Y Kunisaki, H Pierce, Z Wang… - Nature cell …, 2017 - nature.com
Arterioles and sinusoids of the bone marrow (BM) are accompanied by stromal cells that
express nerve/glial antigen 2 (NG2) and leptin receptor (LepR), and constitute specialized …

The patient-as-partner approach in health care: a conceptual framework for a necessary transition

P Karazivan, V Dumez, L Flora, MP Pomey… - Academic …, 2015 - journals.lww.com
The prevalence of chronic diseases today calls for new ways of working with patients to
manage their care. Although patient-centered approaches have contributed to significant …

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures

Q Duan, C Flynn, M Niepel, M Hafner… - Nucleic acids …, 2014 - academic.oup.com
Abstract For the Library of Integrated Network-based Cellular Signatures (LINCS) project
many gene expression signatures using the L1000 technology have been produced. The …