User profiles for "author:Nicholas Rattray"

Nicholas JW Rattray

Senior Lecturer in Clinical Metabolism
Verified email at strath.ac.uk
Cited by 2975

Inside help: an integrative review of champions in healthcare-related implementation

EJ Miech, NA Rattray, ME Flanagan… - SAGE open …, 2018 - journals.sagepub.com
Background/aims: The idea that champions are crucial to effective healthcare-related
implementation has gained broad acceptance; yet the champion construct has been …

Taking your breath away: metabolomics breathes life in to personalized medicine

NJW Rattray, Z Hamrang, DK Trivedi, R Goodacre… - Trends in …, 2014 - cell.com
Breath-based metabolomics (breathomics) is an exciting developing area of biotechnology
that centers on the capture, identification, and quantification of volatile organic compound …

[HTML][HTML] Beyond genomics: understanding exposotypes through metabolomics

NJW Rattray, NC Deziel, JD Wallach, SA Khan… - Human genomics, 2018 - Springer
Background Over the past 20 years, advances in genomic technology have enabled
unparalleled access to the information contained within the human genome. However, the …

[HTML][HTML] An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

P Carbonell, AJ Jervis, CJ Robinson, C Yan… - Communications …, 2018 - nature.com
The microbial production of fine chemicals provides a promising biosustainable
manufacturing solution that has led to the successful production of a growing catalog of …

New cofactor supports α, β-unsaturated acid decarboxylation via 1, 3-dipolar cycloaddition

KAP Payne, MD White, K Fisher, B Khara, SS Bailey… - Nature, 2015 - nature.com
The bacterial ubiD and ubiX or the homologous fungal fdc1 and pad1 genes have been
implicated in the non-oxidative reversible decarboxylation of aromatic substrates, and play a …

UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis

MD White, KAP Payne, K Fisher, SA Marshall, D Parker… - Nature, 2015 - nature.com
Ubiquinone (also known as coenzyme Q) is a ubiquitous lipid-soluble redox cofactor that is
an essential component of electron transfer chains. Eleven genes have been implicated in …

Systems biology guided by XCMS Online metabolomics

T Huan, EM Forsberg, D Rinehart, CH Johnson… - Nature …, 2017 - nature.com
An aim of systems biology is to understand complex interactions between genes, proteins
and metabolites by integrating and modeling multiple data sources. We report an'integrated …

Kynurenic acid may underlie sex-specific immune responses to COVID-19

Y Cai, DJ Kim, T Takahashi, DI Broadhurst, H Yan… - Science …, 2021 - science.org
Coronavirus disease 2019 (COVID-19) has poorer clinical outcomes in males than in
females, and immune responses underlie these sex-related differences. Because immune …

[HTML][HTML] Electronic cigarette exposure triggers neutrophil inflammatory responses

A Higham, NJW Rattray, JA Dewhurst, DK Trivedi… - Respiratory …, 2016 - Springer
Background The use of electronic cigarettes (e-cigs) is increasing and there is widespread
perception that e-cigs are safe. E-cigs contain harmful chemicals; more research is needed …

[HTML][HTML] Meat, the metabolites: An integrated metabolite profiling and lipidomics approach for the detection of the adulteration of beef with pork

DK Trivedi, KA Hollywood, NJW Rattray, H Ward… - Analyst, 2016 - pubs.rsc.org
Adulteration of high quality food products with sub-standard and cheaper grades is a world-
wide problem taxing the global economy. Currently, many traditional tests suffer from poor …