Therapeutic drug monitoring of biologics in inflammatory bowel disease: unmet needs and future perspectives

K Papamichael, W Afif, D Drobne… - The lancet …, 2022 - thelancet.com
Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimising the use of
biologics, and in particular anti-tumour necrosis factor (anti-TNF) therapy, in inflammatory …

How does Helicobacter pylori cause mucosal damage? Its effect on acid and gastrin physiology

J Calam, A Gibbons, ZV Healey, P Bliss, N Arebi - Gastroenterology, 1997 - Elsevier
Helicobacter pylori infection increases gastric acid secretion in patients with duodenal ulcers
but diminishes acid output in patients with gastric cancer and their relatives. Investigation of …

East–West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort

J Burisch, N Pedersen, S Čuković-Čavka, M Brinar… - Gut, 2014 - gut.bmj.com
Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern
Europe. The reasons for these changes remain unknown. The aim of this study was to …

Natural disease course of Crohn's disease during the first 5 years after diagnosis in a European population-based inception cohort: an Epi-IBD study

J Burisch, G Kiudelis, L Kupcinskas, HAL Kievit… - Gut, 2019 - gut.bmj.com
Objective The Epi-IBD cohort is a prospective population-based inception cohort of
unselected patients with inflammatory bowel disease from 29 European centres covering a …

Natural disease course of ulcerative colitis during the first five years of follow-up in a European population-based inception cohort—an Epi-IBD study

J Burisch, KH Katsanos… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background and Aims Few population-based cohort studies have assessed the
disease course of ulcerative colitis [UC] in the era of biological therapy and widespread use …

Dynamic patient position changes during colonoscope withdrawal increase adenoma detection: a randomized, crossover trial

JE East, P Bassett, N Arebi, S Thomas-Gibson… - Gastrointestinal …, 2011 - Elsevier
BACKGROUND:: Colonoscopy has a miss rate for adenomas that may partly relate to poor
visualization of the colonic surface. Dynamic position changes during colonoscope …

Systematic review with meta‐analysis: IBD‐associated colonic dysplasia prognosis in the videoendoscopic era (1990 to present)

M Kabir, R Fofaria, N Arebi, P Bassett… - Alimentary …, 2020 - Wiley Online Library
Background Introduction The prognosis of dysplasia in patients with IBD is largely
determined from observational studies from the pre‐videoendoscopic era (pre‐1990s) that …

Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe—An ECCO-EpiCom study

J Burisch, N Pedersen, S Cukovic-Cavka… - Journal of Crohn's …, 2014 - academic.oup.com
Abstract Background and Aims The incidence of inflammatory bowel disease (IBD) is
increasing in Eastern Europe possibly due to changes in environmental factors towards a …

[HTML][HTML] Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled …

C Mowat, I Arnott, A Cahill, M Smith… - The lancet …, 2016 - thelancet.com
Background Up to 60% of patients with Crohn's disease need intestinal resection within the
first 10 years of diagnosis, and postoperative recurrence is common. We investigated …

Health-care costs of inflammatory bowel disease in a pan-European, community-based, inception cohort during 5 years of follow-up: a population-based study

J Burisch, H Vardi, D Schwartz, M Friger… - The lancet …, 2020 - thelancet.com
Background Inflammatory bowel disease (IBD) places a significant burden on health-care
systems because of its chronicity and need for expensive therapies and surgery. With …