Development and validation of an HPLC–MS/MS method to simultaneously quantify brigatinib, lorlatinib, pralsetinib and selpercatinib in human K2‐EDTA plasma

JL Gulikers, AJ van Veelen… - Biomedical …, 2023 - Wiley Online Library
A liquid chromatography–tandem mass spectrometry method was developed and validated
to quantify the small‐molecule inhibitors (SMIs) brigatinib, lorlatinib, pralsetinib and …

Experiences with Lean Six Sigma as improvement strategy to reduce parenteral medication administration errors and associated potential risk of harm

A van de Plas, M Slikkerveer, S Hoen… - BMJ Open …, 2017 - bmjopenquality.bmj.com
In this controlled before-after study the effect of improvements, derived from Lean Six Sigma
strategy, on parenteral medication administration errors and the potential risk of harm was …