Effect of aspirin and NSAIDs on risk and survival from colorectal cancer
FVN Din, E Theodoratou, SM Farrington, A Tenesa… - Gut, 2010 - gut.bmj.com
Background Previous studies have shown that aspirin and other non-steroidal anti-
inflammatory drugs (NSAIDs) lower colorectal cancer (CRC) risk. However, the lowest …
inflammatory drugs (NSAIDs) lower colorectal cancer (CRC) risk. However, the lowest …
[HTML][HTML] The effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials
PG Vaughan-Shaw, LF Buijs, JP Blackmur… - British journal of …, 2020 - nature.com
Background Low circulating vitamin D levels are associated with poor colorectal cancer
(CRC) survival. We assess whether vitamin D supplementation improves CRC survival …
(CRC) survival. We assess whether vitamin D supplementation improves CRC survival …
Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells
FVN Din, A Valanciute, VP Houde, D Zibrova… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Aspirin reduces the incidence of and mortality from colorectal
cancer (CRC) by unknown mechanisms. Cancer cells have defects in signaling via the …
cancer (CRC) by unknown mechanisms. Cancer cells have defects in signaling via the …
Plasma vitamin D concentration influences survival outcome after a diagnosis of colorectal cancer
Purpose We investigated whether the plasma level of 25-hydroxyvitamin D (25-OHD) after a
diagnosis of colorectal cancer (CRC) influences survival outcome. Patients and Methods We …
diagnosis of colorectal cancer (CRC) influences survival outcome. Patients and Methods We …
[HTML][HTML] Glycosylation of plasma IgG in colorectal cancer prognosis
In this study we demonstrate the potential value of Immunoglobulin G (IgG) glycosylation as
a novel prognostic biomarker of colorectal cancer (CRC). We analysed plasma IgG glycans …
a novel prognostic biomarker of colorectal cancer (CRC). We analysed plasma IgG glycans …
Long term effect of surgery and radiotherapy for colorectal cancer on defecatory function and quality of life
G Knowles, R Haigh, C McLean, HA Phillips… - European Journal of …, 2013 - Elsevier
Purpose Survival from rectal cancer has improved substantially. Understanding the
consequences of treatment is important to optimise patient support and minimise impact on …
consequences of treatment is important to optimise patient support and minimise impact on …
[HTML][HTML] Performance of prediction models on survival outcomes of colorectal cancer with surgical resection: a systematic review and meta-analysis
Prediction models allow accurate estimate of individualized prognosis. Increasing numbers
of models on survival of CRC patients with surgical resection are being published. However …
of models on survival of CRC patients with surgical resection are being published. However …
[HTML][HTML] Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis
Vitamin D deficiency has been associated with several common diseases, including cancer
and is being investigated as a possible risk factor for these conditions. We reported the …
and is being investigated as a possible risk factor for these conditions. We reported the …
Associations between dietary and lifestyle risk factors and colorectal cancer in the Scottish population
E Theodoratou, SM Farrington, A Tenesa… - European journal of …, 2014 - journals.lww.com
Colorectal cancer (CRC) accounts for 9.7% of all cancer cases and for 8% of all cancer-
related deaths. Established risk factors include personal or family history of CRC as well as …
related deaths. Established risk factors include personal or family history of CRC as well as …
[HTML][HTML] Statin use and association with colorectal cancer survival and risk: case control study with prescription data linkage
F Lakha, E Theodoratou, SM Farrington, A Tenesa… - BMC cancer, 2012 - Springer
Abstract Background In Scotland colorectal cancer (CRC) is the third most common cancer
and a leading cause of cancer death. Epidemiological studies have reported conflicting …
and a leading cause of cancer death. Epidemiological studies have reported conflicting …