Sepsis-associated encephalopathy (SAE) refers to a clinical spectrum of acute neurological
dysfunction that arises in the context of sepsis. Although the pathophysiology of SAE is …

Background Chronic subdural haematoma (cSDH) is a common neurosurgical pathology
frequently occurring in older patients. The impact of population ageing on cSDH caseload …

Introduction Cardiopulmonary exercise testing (CPET) is widely used within the United
Kingdom for preoperative risk stratification. Despite this, CPET's performance in predicting …

Background Degenerative cervical myelopathy (DCM) is a poorly recognised form of spinal
cord injury which arises when degenerative changes in the cervical spine injure the spinal …

The COVID-19 pandemic has led to unprecedented strain on intensive care unit (ICU)
admission in parts of the world. Strategies to create surge ICU capacity require complex …

Introduction Chronic subdural haematoma (cSDH) tends to occur in older patients, often with
significant comorbidity. The incidence and effect of medical complications as well as the …

Introduction A chronic subdural haematoma (cSDH) is a collection of altered blood products
between the dura and brain resulting in a slowly evolving neurological deficit. It is …

Background Chronic subdural haematoma (CSDH) is increasingly common. Although
treatment is triaged and provided by neurosurgery, the role of non-operative care, alongside …

The Directed Acyclic Graph (DAG) is a graph representing causal pathways for informing the
conduct of an observational study. The use of DAGs allows transparent communication of a …

Diabetes mellitus (DM) is a group of metabolic conditions characterized by hyperglycaemia.
It is the most common metabolic condition in the world, and the incidence is increasing. In …