User profiles for "author:Daniel Fletcher"
Daniel A FletcherChatterjee Professor of Bioengineering & Biophysics, UC Berkeley Verified email at berkeley.edu Cited by 21847 |
Cell mechanics and the cytoskeleton
DA Fletcher, RD Mullins - Nature, 2010 - nature.com
The ability of a eukaryotic cell to resist deformation, to transport intracellular cargo and to
change shape during movement depends on the cytoskeleton, an interconnected network of …
change shape during movement depends on the cytoskeleton, an interconnected network of …
Use the force: membrane tension as an organizer of cell shape and motility
Many cell phenomena that involve shape changes are affected by the intrinsic deformability
of the plasma membrane (PM). Far from being a passive participant, the PM is now known to …
of the plasma membrane (PM). Far from being a passive participant, the PM is now known to …
Stiffness sensing by cells
PA Janmey, DA Fletcher… - Physiological …, 2020 - journals.physiology.org
Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …
signals are important elements in normal tissue development as well as in disease initiation …
[HTML][HTML] Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
JD MacMicking, C Nathan, G Hom, N Chartrain… - Cell, 1995 - cell.com
Mice deficient in inducible nitric oxide synthase (iNOS) were generated to test the idea that!
NOS defends the host against infectious agents and tumor cells at the risk of contributing to …
NOS defends the host against infectious agents and tumor cells at the risk of contributing to …
[PDF][PDF] Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy
The December 2019 outbreak of a novel respiratory virus, SARS-CoV-2, has become an
ongoing global pandemic due in part to the challenge of identifying symptomatic …
ongoing global pandemic due in part to the challenge of identifying symptomatic …
[HTML][HTML] Mobile phone based clinical microscopy for global health applications
Light microscopy provides a simple, cost-effective, and vital method for the diagnosis and
screening of hematologic and infectious diseases. In many regions of the world, however …
screening of hematologic and infectious diseases. In many regions of the world, however …
Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis
SS Justice, C Hung, JA Theriot… - Proceedings of the …, 2004 - National Acad Sciences
Uropathogenic Escherichia coli (UPEC) are capable of forming complex intracellular
bacterial communities (IBC) within the superficial umbrella cells of the bladders of C3H and …
bacterial communities (IBC) within the superficial umbrella cells of the bladders of C3H and …
Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures
CM Nelson, MM VanDuijn, JL Inman, DA Fletcher… - Science, 2006 - science.org
The treelike structures of many organs, including the mammary gland, are generated by
branching morphogenesis, a reiterative process of branch initiation and invasion from a …
branching morphogenesis, a reiterative process of branch initiation and invasion from a …
[HTML][HTML] Force microscopy of nonadherent cells: a comparison of leukemia cell deformability
Atomic force microscopy (AFM) has become an important tool for quantifying mechanical
properties of biological materials ranging from single molecules to cells and tissues. Current …
properties of biological materials ranging from single molecules to cells and tissues. Current …
Membrane bending by protein–protein crowding
JC Stachowiak, EM Schmid, CJ Ryan, HS Ann… - Nature cell …, 2012 - nature.com
Curved membranes are an essential feature of dynamic cellular structures, including
endocytic pits, filopodia protrusions and most organelles,. It has been proposed that …
endocytic pits, filopodia protrusions and most organelles,. It has been proposed that …