Diagnosis and management of primary hyperparathyroidism

CY Zhu, C Sturgeon, MW Yeh - Jama, 2020 - jamanetwork.com
The adoption of routine chemistry panel testing in the 1970s led to increased discovery of
PHPT and changed its clinical presentation in developed nations from a rare, highly …

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

T Masuda, X Wang, M Maeda, MC Canver, F Sher… - Science, 2016 - science.org
Genes encoding human β-type globin undergo a developmental switch from embryonic to
fetal to adult-type expression. Mutations in the adult form cause inherited …

Effectiveness of molecular testing techniques for diagnosis of indeterminate thyroid nodules: a randomized clinical trial

MJ Livhits, CY Zhu, EJ Kuo, DT Nguyen, J Kim… - JAMA …, 2021 - jamanetwork.com
Importance Approximately 20% of thyroid nodules display indeterminate cytology. Molecular
testing can refine the risk of malignancy and reduce the need for diagnostic …

[HTML][HTML] Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis

Y Han, J Byun, C Zhu, R Sun, JY Roh… - Nature …, 2023 - nature.com
Primary sclerosing cholangitis (PSC) is a rare autoimmune bile duct disease that is strongly
associated with immune-mediated disorders. In this study, we implemented multitrait joint …

HIV-associated Burkitt lymphoma: outcomes from a US-UK collaborative analysis

JP Alderuccio, AJ Olszewski, AM Evens… - Blood …, 2021 - ashpublications.org
Data addressing prognostication in patients with HIV related Burkitt lymphoma (HIV-BL)
currently treated remain scarce. We present an international analysis of 249 (United States …

Burkitt lymphoma international prognostic index

AJ Olszewski, LH Jakobsen, GP Collins… - Journal of clinical …, 2021 - ascopubs.org
PURPOSE Burkitt lymphoma (BL) has unique biology and clinical course but lacks a
standardized prognostic model. We developed and validated a novel prognostic index …

Fexofenadine and rosuvastatin pharmacokinetics in mice with targeted disruption of organic anion transporting polypeptide 2B1

S Medwid, MMJ Li, MJ Knauer, K Lin, SE Mansell… - Drug Metabolism and …, 2019 - ASPET
Organic anion transporting polypeptide 2B1 (OATP2B1) is a widely expressed membrane
transporter with diverse substrate specificity. In vitro and clinical studies suggest a role for …

[PDF][PDF] Origin of immunoglobulin isotype switching

C Zhu, V Lee, A Finn, K Senger, AA Zarrin… - Current Biology, 2012 - cell.com
Background From humans to frogs, immunoglobulin class switching introduces different
effector functions to antibodies through an intrachromosomal DNA recombination process at …

Correlation of ThyroSeq results with surgical histopathology in cytologically indeterminate thyroid nodules

PD Chin, CY Zhu, DP Sajed, GA Fishbein, MW Yeh… - Endocrine …, 2020 - Springer
The ThyroSeq next-generation sequencing test refines the risk of malignancy in cytologically
indeterminate thyroid nodules. Specific genetic alterations have distinct cancer probabilities …

Trends in the surgical management of known or suspected differentiated thyroid cancer at a single institution, 2010–2018

CY Zhu, S Sha, CH Tseng, SE Yang, LE Orr, M Levin… - Thyroid, 2020 - liebertpub.com
Background: The surgical management of nodular thyroid disease has been influenced by
the advent of molecular diagnostics and recent guidelines recommending a more …