Non‐T2 asthma is traditionally defined as asthma without features of T2 asthma. The
definition is arbitrary and is generally based on the presence of neutrophils in sputum, or the …

Airway Eosinophilopoietic and Autoimmune Mechanisms of Eosinophilia in Severe Asthma -
Immunology and Allergy Clinics Skip to Main Content Advertisement Immunology and Allergy …

Biologic therapies in asthma are indicated in severe disease, and they are directed against
specific inflammatory modulators that contribute to pathogenesis and severity. Currently …

Background In clinical trials, the two anti-interleukin (IL)-5 monoclonal antibodies (mAbs:
mepolizumab and reslizumab) approved to treat severe eosinophilic asthma reduce …

To the Editor, There is paucity of data on immune responses to COVID-19 in severe
asthmatics treated with biologics. Recent guidelines recommend continuing these agents …

Background Excess pulmonary iron has been implicated in the pathogenesis of lung
disease, including asthma and COPD. An association between higher iron content in …

Background We previously showed in patients with poorly controlled eosinophilic asthma
that a single dose of benralizumab resulted in significantly improved Asthma Control …

Rationale and Objectives The minimal clinically important difference (MCID) and upper limit
of normal (ULN) for MRI ventilation defect percent (VDP) were previously reported for …

Abstract Rationale On Wright-stained sputum cytospins, eosinophil differential of≥ 1.2% is
considered abnormal, and≥ 2.3% identifies an eosinophilic endotype. We hypothesized …

Effect of dupilumab on sputum eosinophils in patients with moderate-to-severe asthma Effect of
dupilumab on sputum eosinophils in patients with moderate-to-severe asthma Allergy. 2024 …