Glutathione-S-transferase family of enzymes
RC Strange, MA Spiteri, S Ramachandran… - … Molecular Mechanisms of …, 2001 - Elsevier
The loci encoding the glutathione-S-transferase (GST) enzymes comprise a large
supergene family located on at least seven chromosomes. The function of the GST enzymes …
supergene family located on at least seven chromosomes. The function of the GST enzymes …
Preeclampsia and future cardiovascular health: a systematic review and meta-analysis
Background—Preeclampsia is a pregnancy-specific disorder resulting in hypertension and
multiorgan dysfunction. There is growing evidence that these effects persist after pregnancy …
multiorgan dysfunction. There is growing evidence that these effects persist after pregnancy …
Glutathione S-transferase: genetics and role in toxicology
RC Strange, PW Jones, AA Fryer - Toxicology letters, 2000 - Elsevier
The glutathione S-transferases (GST) are a supergene family of dimeric, enzymes that
catalyse the conjugation of glutathione (GSH) to a variety of electrophiles including arene …
catalyse the conjugation of glutathione (GSH) to a variety of electrophiles including arene …
Vascular endothelial growth factor gene polymorphisms are associated with acute renal allograft rejection
M Shahbazi, AA Fryer, V Pravica… - Journal of the …, 2002 - journals.lww.com
Acute rejection is a major cause of reduced survival of renal allografts. Vascular endothelial
growth factor (VEGF) is a mitogen for endothelial cells and is expressed widely by renal …
growth factor (VEGF) is a mitogen for endothelial cells and is expressed widely by renal …
Polymorphism at the Glutathione S-transferase GSTP1 Locus: A New Marker for Bronchial Hyperresponsiveness and Asthma
Most genetic studies of asthma have concentrated on genes on chromosomes 11q and 5q
and their association with the key asthma-related phenotypes of bronchial …
and their association with the key asthma-related phenotypes of bronchial …
Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancers
M Deakin, J Elder, C Hendrickkse, D Peckham… - 1996 - academic.oup.com
Allelism in glutathione S-transferase GSTM1 and GSTT1 has been suggested as a risk factor
in various cancers. Accordingly, we describe a group of case-control studies carried out to …
in various cancers. Accordingly, we describe a group of case-control studies carried out to …
Association between functional polymorphism in EGF gene and malignant melanoma
M Shahbazi, V Pravica, N Nasreen, H Fakhoury… - The Lancet, 2002 - thelancet.com
Background Malignant melanoma, the most serious cutaneous malignancy, has attracted
substantial attention because of its rapidly increasing incidence and the poor prognosis of …
substantial attention because of its rapidly increasing incidence and the poor prognosis of …
Managing demand for laboratory tests: a laboratory toolkit
AA Fryer, WSA Smellie - Journal of clinical pathology, 2013 - jcp.bmj.com
Healthcare budgets worldwide are facing increasing pressure to reduce costs and improve
efficiency, while maintaining quality. Laboratory testing has not escaped this pressure …
efficiency, while maintaining quality. Laboratory testing has not escaped this pressure …
Clinical risk factors associated with nonmelanoma skin cancer in renal transplant recipients
HM Ramsay, AA Fryer, S Reece, AG Smith… - American journal of …, 2000 - Elsevier
A single-center, cross-sectional, longitudinal study was conducted to determine the
prevalence, annual incidence, and clinical risk factors for skin cancer in a white renal …
prevalence, annual incidence, and clinical risk factors for skin cancer in a white renal …
Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma
PE Hutchinson, JE Osborne, JT Lear, AG Smith… - Clinical Cancer …, 2000 - AACR
Abstract Calcitriol [1, 25 (OH) 2D3], the hormonal derivative of vitamin D3, is an
antiproliferative and prodifferentiation factor for several cell types, including cultured …
antiproliferative and prodifferentiation factor for several cell types, including cultured …