Patients With Uncontrolled Components of Metabolic Syndrome Have Increased Risk of Complications Following Total Joint Arthroplasty
Section snippets
Methods and Materials
Following approval from the institutional review board, the joint arthroplasty database at this institution was utilized to identify those patients undergoing TJA with MetS between April 2000 and December 2007. Several authors have proposed varying definitions of this syndrome [14]. For the purpose of this study, we defined MetS as a body mass index (BMI) greater than 30 kg/m2, as well as a history of dyslipidemia, hypertension, and diabetes.
Control of MetS was assessed by preoperative blood
Results
During the period of time queried, we identified 133 patients who had all four components of MetS. These patients underwent 148 TJAs (103 primary knee, 34 primary hip, 7 revision knee, and 4 revision hip) during 136 admissions. Patients had an average age of 65 years (range: 40–86 years), average BMI of 37 kg/m2 (range: 30–70 kg/m2), and 79 (59%; 79/133) were female.
Within this group, 36 (26.5%; 36/136) patients had at least a single uncontrolled component of MetS. There were seven cases with
Discussion
Total joint arthroplasty is a successful procedure that provides significant relief and return to function for a majority of patients. Nevertheless, severe complications do occur and can require costly work-up and treatments including possible reoperations. Many of these complications–which can include PE, stroke, infection, acute renal failure, and cardiovascular events among many others–have devastating effects on the patient's outcome and general health. Over the past decades, many efforts
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The Conflict of Interest statement associated with this article can be found at http://dx.doi.org/10.1016/j.arth.2012.12.018.