Skip to main content
Log in

Lethal outcome of post-tonsillectomy hemorrhage

  • Head and Neck
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Despite the large number of tonsillectomies performed little knowledge exists about post-tonsillectomy hemorrhage (PTH) with lethal outcome. This study was performed to evaluate clinical features in a larger patient population with emphasis on the onset of this complication. A nationwide collection of cases was performed based on personal communication, expert reports to lawsuits and professional boards, and case reports received after a plea published in a professional national journal. Clinical data of 29 patients were collected of whom the 18 were children (64%). With one exception all patients experienced secondary PTH (>24 h) occurring 1–28 days after tonsillectomy. Aspiration contributed to lethal outcome in 13 cases. Fatalities were unavoidable although 21 patients were in the hospital. Massive vomiting of blood was observed in 11 patients. There were 11 patients without (group A) and 18 with (group B) episodes of repeated bleeding. This study suggests that particularly children are endangered by lethal PTH. Inpatient treatment was unable to prevent lethal outcome in this selected patient population. However, it appears wise to re-admit patients with delayed PTH, since excessive PTH may occur. These unexpected and unpredictable situations require an immediate and adequate medical treatment by a skilled staff. The paucity of data currently does not allow calculation of a cut-off point at which the risk of life-threatening PTH significantly decreases. Secondary PTH remains a substantial complication.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Randall DA, Hoffer ME (1998) Complications of tonsillectomy and adenoidectomy. Otolaryngol Head Neck Surg 118:61–68. doi:10.1016/S0194-5998(98)70376-6

    Article  PubMed  CAS  Google Scholar 

  2. Rasmussen N (1987) Complications of tonsillectomy and adenoidectomy. Otolaryngol Clin North Am 20:383–390

    PubMed  CAS  Google Scholar 

  3. Windfuhr JP (2002) Excessive post-tonsillectomy hemorrhage requiring ligature of the external carotid artery. Auris Nasus Larynx 29:159–164. doi:10.1016/S0385-8146(01)00138-9

    Article  PubMed  Google Scholar 

  4. Mutz I, Simon H (1993) Hemorrhagic complications after tonsillectomy and adenoidectomy. Experiences with 7,743 operations in 14 years. Wien Klin Wochenschr 105:520–522

    PubMed  CAS  Google Scholar 

  5. Chiang TM, Sukis AE, Ross DE (1968) Tonsillectomy performed on an outpatient basis. Report of a series of 40,000 cases performed without a death. Arch Otolaryngol 88:307–310

    PubMed  CAS  Google Scholar 

  6. Fearon B, Strelzow V (1979) Pediatric adenoidectomy and tonsillectomy—personal viewpoints. J Otolaryngol 8:40–48 Medline

    PubMed  CAS  Google Scholar 

  7. Williams RG (1967) Haemorrhage following tonsillectomy and adenoidectomy. (A review of 18,184 operations). J Laryngol Otol 81:805–808. doi:10.1017/S0022215100067712

    Article  PubMed  CAS  Google Scholar 

  8. Kirse DJ, Tryka AF, Seibert RW, Bower CM (1996) Mortality following adenotonsillectomy in a patient with Williams-Campbell syndrome. Arch Otolaryngol Head Neck Surg 122:1007–1010

    PubMed  CAS  Google Scholar 

  9. Peeters A, Claes J, Saldien V (2001) Lethal complications after tonsillectomy. Acta Otorhinolaryngol Belg 55:207–213

    PubMed  CAS  Google Scholar 

  10. McRae RG, Weissburg AJ, Chang KW (1994) Iatrogenic hyponatremia: a cause of death following pediatric tonsillectomy. Int J Pediatr Otorhinolaryngol 30:227–232. doi:10.1016/0165-5876(94)90064-7

    Article  PubMed  CAS  Google Scholar 

  11. Judd BA, Haycock GB, Dalton N, Chantler C (1987) Hyponatraemia in premature babies and following surgery in older children. Acta Paediatr Scand 76:385–393. doi:10.1111/j.1651-2227.1987.tb10487.x

    Article  PubMed  CAS  Google Scholar 

  12. Agut Fuster MA, del Campo Biosca J, Ferrer Rodriguez A, Ramos Martinez MJ, Viel Martinez JM, Agulles Fornes MJ (2006) Post-tonsillectomy hyponatremia: a posible lethal complication. Acta Otorrinolaringol Esp 57:247–250

    PubMed  CAS  Google Scholar 

  13. Donaldson JD, Stool SE (1979) Complications of tonsillectomy and adenoidectomy. In: Conley JJ (ed) Complications of head and neck surgery. Thieme, Stuttgart

  14. Tate N (1963) Deaths from tonsillectomy. Lancet 2:1090–1091. doi:10.1016/S0140-6736(63)92859-9

    Article  PubMed  CAS  Google Scholar 

  15. Alexander DW, Graff TD, Kelley E (1965) Factors in tonsillectomy mortality. Arch Otolaryngol 82:409–411

    PubMed  CAS  Google Scholar 

  16. Cohen D, Dor M (2008) Morbidity and mortality of post-tonsillectomy bleeding: analysis of cases. J Laryngol Otol 122(1):88–92

    Article  PubMed  CAS  Google Scholar 

  17. Pratt LW, Gallagher RA (1979) Tonsillectomy and adenoidectomy: incidence and mortality, 1968–1972. Otolaryngol Head Neck Surg 87:159–166

    PubMed  CAS  Google Scholar 

  18. Pratt LW (1970) Tonsillectomy and adenoidectomy: mortality and morbidity. Trans Am Acad Ophthalmol Otolaryngol 74:1146–1154

    PubMed  CAS  Google Scholar 

  19. Kincaid WH (1962) Retrieval of information from medical records. Am Doc 13:83–85

    Article  Google Scholar 

  20. Dunne AA, Granger O, Folz BJ, Sesterhenn A, Werner JA (2003) Peritonsillar abscess—critical analysis of abscess tonsillectomy. Clin Otolaryngol Allied Sci 28:420–424. doi:10.1046/j.1365-2273.2003.00736.x

    Article  PubMed  CAS  Google Scholar 

  21. Davies DD (1964) Anaesthetic mortality in tonsillectomy and adenoidectomy. Br J Anaesth 36:110–114. doi:10.1093/bja/36.2.110

    Article  PubMed  CAS  Google Scholar 

  22. Carmody D, Vamadevan T, Cooper SM (1982) Post tonsillectomy haemorrhage. J Laryngol Otol 96:635–638. doi:10.1017/S0022215100092926

    Article  PubMed  CAS  Google Scholar 

  23. Windfuhr JP (2002) Excessive post-tonsillectomy hemorrhage requiring ligature of the external carotid artery. Auris Nasus Larynx 29:159–164. doi:10.1016/S0385-8146(01)00138-9

    Article  PubMed  Google Scholar 

  24. SJ Moralee, JA Murray (1995) Would day-case adult tonsillectomy be safe? J Laryngol Otol 109:1166–1167. doi:10.1017/S0022215100132347

    Google Scholar 

  25. Schloss MD, Tan AK, Schloss B, Tewfik TL (1994) Outpatient tonsillectomy and adenoidectomy: complications and recommendations. Int J Pediatr Otorhinolaryngol 30:115–122. doi:10.1016/0165-5876(94)90194-5

    Article  PubMed  CAS  Google Scholar 

  26. Rakover Y, Almog R, Rosen G (1997) The risk of postoperative haemorrhage in tonsillectomy as an outpatient procedure in children. Int J Pediatr Otorhinolaryngol 41:29–36. doi:10.1016/S0165-5876(97)00055-4

    Article  PubMed  CAS  Google Scholar 

  27. Reiner SA, Sawyer WP, Clark KF, Wood MW (1990) Safety of outpatient tonsillectomy and adenoidectomy. Otolaryngol Head Neck Surg 102:161–168

    PubMed  CAS  Google Scholar 

  28. Helmus C, Grin M, Westfall R (1990) Same-day-stay adenotonsillectomy. Laryngoscope 100:593–596. doi:10.1288/00005537-199006000-00008

    Article  PubMed  CAS  Google Scholar 

  29. Mitchell RB, Pereira KD, Friedman NR, Lazar RH (1997) Outpatient adenotonsillectomy. Is it safe in children younger than 3 years? Arch Otolaryngol Head Neck Surg 123:681–683

    PubMed  CAS  Google Scholar 

  30. Tom LW, DeDio RM, Cohen DE, Wetmore RF, Handler SD, Potsic WP (1992) Is outpatient tonsillectomy appropriate for young children? Laryngoscope 102:277–280

    PubMed  CAS  Google Scholar 

  31. American Academy of Otolaryngology-Head and Neck Surgery (1996) Tonsillectomy and adenoidectomy inpatient guidelines. Recommendations of the AAO-HNS Pediatric Otolaryngology Committee. Mosby, St. Louis, pp 1–4

    Google Scholar 

  32. Sanderson BA (1958) Exsanguinating hemorrhage twenty-one days after tonsilloadenoidectomy. AMA Arch Otolaryngol 68:630–631

    PubMed  CAS  Google Scholar 

  33. Dey FL (1968) Late hemorrhage following tonsillectomy. Arch Otolaryngol 87:558

    PubMed  CAS  Google Scholar 

  34. Windfuhr JP (2003) Lethal post-tonsillectomy hemorrhage. Auris Nasus Larynx 30:391–396. doi:10.1016/j.anl.2003.07.004

    Article  PubMed  Google Scholar 

  35. Swoboda H, Welleschik B (1988) A severe late tonsillar hemorrhage 2 months postoperatively. Laryngol Rhinol Otol (Stuttg) 67:431–433

    CAS  Google Scholar 

  36. Leuwer R, Petri S, Schulz F, Püschel K (1998) Deaths from tonsillectomy and adenoidectomy. Laryngo Rhino Otol 77:669–672

    Article  Google Scholar 

  37. Nathan MD, Sessions DG (1981) Massive posttonsillectomy hemorrhage. South Med J 74:1153–1156

    PubMed  CAS  Google Scholar 

  38. Anjaria DJ, Mohr AM, Deitch EA (2008) Haemorrhagic shock therapy. Expert Opin Pharmacother 9:901–911. doi:10.1517/14656566.9.6.901

    Article  PubMed  CAS  Google Scholar 

  39. Medinovic A, Escher F (1979) Blood coagulation tests before adenoido-tonsillectomy? HNO 27:179

    PubMed  CAS  Google Scholar 

  40. Bergquist B (1946) Anomalies in the course of arteria carotis interna in the upper region of the pharynx. Acta Otolaryngol 34:246–255. doi:10.3109/00016484609128379

    Article  Google Scholar 

  41. Carmack J (1929) Aberrant internal carotids and their relation to surgery of the pharynx. Laryngoscope 39:707–720. doi:10.1288/00005537-192911000-00001

    Article  Google Scholar 

  42. Weibel J, Fields W (1965) Tortuosity, coiling and kinking of the internal carotid artery. Neurology 15:7–18

    PubMed  CAS  Google Scholar 

  43. Lowe D, van der Meulen J (2004) Tonsillectomy technique as a risk factor for postoperative haemorrhage. Lancet 364:697–702. doi:10.1016/S0140-6736(04)16896-7

    Article  PubMed  CAS  Google Scholar 

  44. Gardner JF (1968) Sutures and disasters in tonsillectomy. Arch Otolaryngol 88:551–555

    PubMed  CAS  Google Scholar 

  45. Sholevar J, Hunsicker R, Stools S (1972) Arteriography in posttonsillectomy hemorrhage. Arch Otolaryngol 95:581–583

    Google Scholar 

  46. Simoni P, Bello JA, Kent B (2001) Pseudoaneurysm of the lingual artery secondary to tonsillectomy treated with selective embolization. Int J Pediatr Otorhinolaryngol 59:125–128. doi:10.1016/S0165-5876(01)00478-5

    Article  PubMed  CAS  Google Scholar 

  47. Hertzanu Y, Hirsch M, Tovi F (1987) Pseudoaneurysm of internal carotid artery secondary to tonsillectomy: combined radiologic and surgical treatment. Cardiovasc Intervent Radiol 10:147–149. doi:10.1007/BF02577990

    Article  PubMed  CAS  Google Scholar 

  48. Windfuhr JP (2002) Indications for interventional arteriography in post-tonsillectomy hemorrhage. J Otolaryngol 31:18–22. doi:10.2310/7070.2002.19160

    Article  PubMed  Google Scholar 

  49. Paulsen F, Tillmann B, Christofides C, Richter W, Koebke J (2000) Curving and looping of the internal carotid artery in relation to the pharynx: frequency, embryology and clinical implications. J Anat 197:373–381. doi:10.1046/j.1469-7580.2000.19730373.x

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

The authors thank Albrecht Wienke, Corporate Counsel of the Deutsche Gesellschaft für HNO-Heilkunde in Cologne, Germany, for his excellent support.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J. P. Windfuhr.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Windfuhr, J.P., Schloendorff, G., Baburi, D. et al. Lethal outcome of post-tonsillectomy hemorrhage. Eur Arch Otorhinolaryngol 265, 1527–1534 (2008). https://doi.org/10.1007/s00405-008-0699-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-008-0699-4

Keywords

Navigation