Table 2

Hierarchy of evidence

Level IEvidence based on systematic reviews or meta-analyses of RCTs; clinical guidelines based on systematic reviews or meta-analyses
Level IIEvidence collected on well-designed RCTs
Level IIIEvidence from non-RCTs
Level IVEvidence from well-designed cohort and case-control studies
Level VEvidence from systematic reviews of qualitative and descriptive studies
Level VIEvidence from qualitative and descriptive studies
Level VIIEvidence from expert opinions and/or reports of expert committees
  • RCTs, randomised controlled trials.