Table 2

Predicted probability of outcome between automated refills and usual care patients, controlling for baseline differences*

Usual care
Mean (95% CI)
Automated refills
Mean (95% CI)
Difference (95% CI)P value
Intention to treat
 HgbA1C<8, %60.5 (51.5 to 69.5)60.8 (52.3 to 69.4)−0.3 (−12.1 to 12.8)0.96
 HgbA1C, mean7.9 (7.6 to 8.1)7.8 (7.6 to 8.1)−0.04 (−0.42 to 0.34)0.84
 MPR DM57.1 (52.5 to 61.6)62.2 (56.2 to 68.2)5.1 (−2.9 to 13.1)0.21
 MPR reference54.5 (50.2 to 58.7)63.9 (59.3 to 68.6)9.5 (3.1 to 15.9)<0.01
Per protocol
 HgbA1C<8, %60.6 (51.4 to 69.8)53.6 (40.4 to 66.8)−7.0 (−23.6 to 9.5)0.39
 HgbA1C, mean7.9 (7.6 to 8.2)8.1 (7.7 to 8.6)0.3 (−0.3 to 0.8)0.33
 MPR DM57.3 (53.0 to 61.7)76.4 (69.1 to 83.8)19.1 (10.1 to 28.1)<0.001
 MPR reference54.1 (50.0 to 58.3)71.4 (62.7 to 80.0)17.2 (7.5 to 26.9)0.001
  • *Controlling for patient age, race, preintervention primary care visit number, disability rating and primary care clinic affiliation in quarter prior to project. Glycaemic measures also control for baseline A1C in 12 months prior. Medication measures also control for baseline MPR in 6 months prior.

  • DM, diabetes mellitus; MPR, medication possession ratio.