Gastroprotection prescribed | Audit 1 | Audit 2 | P value | ||
N | % | N | % | ||
Proton-pump inhibitor | 70 484 | 77.2 | 60 884 | 82.3 | <0.001 |
H2 receptor antagonist | 2747 | 3.0 | 1817 | 2.5 | <0.001 |
Misoprostol | 407 | 0.4 | 170 | 0.2 | |
Total with gastroprotection | 73 638 | 80.7 | 62 871 | 85.0 | <0.001 |
Referral of patients without gastroprotection | |||||
Total without gastroprotection | 17 614 | 19.3 | 11 121 | 15.0 | |
Current or recent referral | 10 358 | 58.8 | 7512 | 67.5 | <0.001 |
Referral of patients co-prescribed antiplatelets, anticoagulants or SSRIs without gastroprotection (audit 1, n=16 999*; audit 2, n=12 807*) | |||||
Total with gastroprotection | 14 556 | 85.6 | 11 370 | 88.8 | <0.001 |
Total without gastroprotection | 2443 | 14.4 | 1437 | 11.2 | |
Current or recent referral | 1618 | 66.2 | 1099 | 76.5 | <0.001 |
*Some instances where more than one medicine class concurrently prescribed.
SSRIs, selective serotonin reuptake inhibitors.