Comparison of baseline characteristics between control and intervention groups
| Variable | Control | Intervention | P value |
| Males | 324/651 (49.77%) | 203/411 (49.39%) | 0.95 |
| Age | |||
| Mean (SD) | 61.25 (17.57) | 61.34 (17.39) | 0.94 |
| Median (IQR) | 62.0 (50.0–75.0) | 63.0 (50.0–75.0) | 0.93 |
| Primary admitting diagnosis | |||
| 1. Ischaemic stroke | 219/651 (33.64%) | 110/411 (26.76%) | 0.02 |
| 2. ICH | 109/651 (16.74%) | 45/411 (10.95%) | 0.009 |
| 3. SAH | 55/651 (8.45%) | 34/411 (8.27%) | 1 |
| 4. Subdural haematoma | 52/651 (7.99%) | 38/411 (9.25%) | 0.5 |
| 5. Status epilepticus/seizures | 83/651 (12.75%) | 43/411 (10.46%) | 0.28 |
| 6. Tumour resection | 92/651 (14.13%) | 129/411 (31.39%) | <0.001 |
| 7. Encephalopathy | 15/651 (2.30%) | – | <0.001 |
| 8. Cord compression | 26/651 (3.99%) | 12/411 (2.92%) | 0.4 |
| SOFA | |||
| Mean (SD) | 2.84 (2.78) | 2.58 (2.68) | 0.13 |
| Median (IQR) | 2.0 (1.0–4.0) | 2.0 (0.0–4.0) | 0.11 |
ICH, intracerebral haemorrhage; SAH, subarachnoid haemorrhage; SOFA, Sequential Organ Failure Assessment.