NSAID use in patients without contraindications
| 2016 | 2019 | P value | |
| Patients prescribed NSAID (per cent) | 21 (26.6) | 31 (59.6) | <0.001 |
| THA | 12 (32.4) | 14 (63.6) | 0.03 |
| TKA | 9 (19.1) | 17 (56.7) | 0.003 |
Contraindications to NSAID use included estimated glomerular filtration rate (eGFR) <60 mL/min, prior adverse reaction, use of medications active on the renin–angiotensin–aldosterone axis, diuretics, anticoagulants and prior history of gastric ulceration.
NSAID, non-steroidal anti-inflammatory drug; THA, total hip arthroplasty; TKA, total knee arthroplasty.