Distribution of HMX events by drug category
| Drug category | Infusions | DERS infusions | HMX events | HMX incidence (% from ALL infusions) (%; 95% CI) | HMX incidence (% from DERS infusions) (%, 95% CI) |
| Antiepileptics | 5269 | 3068 | 177 | 3.36 (2.91 to 3.88) | 5.77 (5.0 to 6.65) |
| Antiviral drugs | 10 582 | 4882 | 235 | 2.22 (1.96 to 2.52) | 4.81 (4.25 to 5.45) |
| Poisoning antidotes | 6542 | 2325 | 98 | 1.5 (1.23 to 1.82) | 4.22 (3.47 to 5.11) |
| Calcium and magnesium | 29 243 | 16 897 | 535 | 1.83 (1.68 to 1.99) | 3.17 (2.91 to 3.44) |
| Loop diuretics | 11 711 | 5484 | 131 | 1.12 (0.94 to 1.33) | 2.39 (2.02 to 2.83) |
| Potassium chloride | 86 746 | 32 504 | 749 | 0.86 (0.8 to 0.93) | 2.3 (2.15 to 2.47) |
| Antibacterial drugs | 279 633 | 134 821 | 2979 | 1.06 (1.0 to 1.1) | 2.21 (2.13 to 2.29) |
| Vitamins and minerals | 20 160 | 9794 | 190 | 0.94 (0.82 to 1.09) | 1.94 (1.69 to 2.23) |
| Insulin | 33 177 | 6644 | 85 | 0.26 (0.21 to 0.32) | 1.28 (1.04 to 1.58) |
| Non-opioid analgesics | 72 119 | 38 860 | 179 | 0.25 (0.21 to 0.29) | 0.46 (0.4 to 0.53) |
| All other drug categories | 189 988 | 82 984 | 709 | 0.37 (0.35 to 0.4) | 0.85 (0.79 to 0.92) |
| Total | 745 170 | 338 263 | 6067 | 0.81 (0.79 to 0.83) | 1.79 (1.75 to 1.84) |
Top 10 by prevalence with aggregated figures for all others. See online supplemental file 3 for details of all drug categories.
DERS, drug error reduction software; HMX, hard maximum.