Proportion of children with SIGNS items present prior to index event
| SIGNS category | SIGNS subcategory | Item N (%) | Category N (%) | Hours prior to index event median (IQR) |
| Behaviour | Reduced interaction | 7 (14) | 22 (44) | 24.0 (8.3–43.8) |
| Reduced independent actions | 16 (32) | |||
| Abnormal or lack of movement | 2 (4) | |||
| Breathing | Noticeable breathing | 20 (40) | 26 (52) | 36.0 (8.3–49.5) |
| Long pauses between breaths | 6 (12) | |||
| Skin | Jaundice in the first month of life | 0 (0) | 10 (20) | 8.5 (6.3–18.0) |
| Mottled and cold skin (and other) | 10 (20) | |||
| Blue(ish) skin and tongue | 1 (2) | |||
| Purple rash | 0 (0) | |||
| Fluids | Persistent vomiting | 7 (14) | 21 (42) | 24.0 (7.0–55.0) |
| Colourful vomiting | 3 (6) | |||
| Minimal fluid intake | 13 (26) | |||
| Not passing urine | 3 (6) | |||
| Treatment | No treatment response | 1 (2) | 1 (2) | |
| Any | 48 (96) | 24.0 (9.0–48.5) |
SIGNS, Severe Illness Getting Noticed Sooner.