GCP | FCP | |
Hypoglycaemia threshold | ≤2.5 mmol/L | <3 mmol/L |
Screening eligibility criteria | Infants of diabetic mothers. LGA (BW ≥4000 g). Term ≥37 weeks with BW ≤2270 g. Preterm 35–37 weeks with BW ≥1800 g. | Infants of diabetic mothers. LGA (BW >4000 g or >90 th centile). Term ≥37 weeks with <2600 g. Preterm 35–37 weeks with BW ≥1800 g. Infants of obese mothers (>85 kg or BMI >33 kg/m2). |
Timing of capillary glucose monitoring | 0, 1, 3, 6, 12 and 24 hours of age. | 2, 6, 12, 18 and 24 hours of age for AGA and LGA infants. SGA infants have an additional test at 36 hours. |
Approach to intervention | Formula feeds, then IV dextrose, then IV glucagon and/or hydrocortisone. | Skin-to-skin care and breast feeding soon after birth. Emphasis on feeding in the first 2 hours. First glucose check at 2 hours of life. When glucose levels were suboptimal, glucose gel followed by feeding. |
Admission to SCN criteria | Infants of diabetic mothers irrespective of capillary glucose levels. Infants with capillary glucose ≤2.5 mmol/L irrespective of feeding status. | Infants who are unable to maintain glucose ≥3 mmol/L after glucose gel and feeds. Infants born to a diabetic mother on insulin therapy and with weight >4000 g (or >90 th centile). |
Excluded infants | Infants with birth weight <1800 g. Infants <35 weeks gestation. Infants requiring direct level 4 care. Infants who are out born. Infants admitted to SCN for non-hypoglycaemia reasons. |
AGA, appropriate for gestational age; BMI, body mass index; BW, birth weight; FCP, feed-centric pathway; GCP, glucose-centric pathway; IV, intravenous; LGA, large for gestational age; SCN, special care nursery; SGA, small-for-gestational-age.