Table 1

Indication for antibiotics (categorised according to hospital guideline)

IndicationPre-PDSA
n (%)
PDSA 1
n (%)
PDSA 2
n (%)
PDSA 3
n (%)
Post-PDSA
n (%)
Total
n (%)
P value*
Complicated† appendicitis or intra-abdominal collection12 (24)12 (23.1)14 (22.2)25 (25)8 (23.5)71 (23.7)0.96
Pneumonia14 (28)7 (13.5)18 (28.6)12 (12)9 (26.5)60 (20.1)0.13
Preseptal cellulitis4 (8)8 (15.4)5 (7.9)17 (17)2 (5.9)36 (12)0.34
Appendicitis, uncomplicated1 (2)1 (1.9)1 (1.6)19 (19)5 (14.7)27 (9)0.06
Urinary tract infection4 (8)5 (9.6)5 (7.9)5 (5)4 (11.8)23 (7.7)0.92
Cellulitis4 (8)4 (7.7)1 (1.6)8 (8)2 (5.9)19 (6.4)0.6
Acute cervical lymphadenitis2 (4)4 (7.7)7 (11.1)2 (2)3 (8.8)18 (6)0.51
Pyelonephritis4 (8)3 (5.8)4 (6.4)1 (1)012 (4)0.12
Skin abscesses and boils1 (2)2 (3.9)06 (6)09 (3)0.65
Pleural empyema01 (1.9)2 (3.2)1 (1)04 (1.3)0.37
Tonsillitis0004 (4)04 (1.3)0.37
Acute osteomyelitis1 (2)1 (1.9)0002 (0.7)0.21
Orbital cellulitis001 (1.6)01 (2.9)2 (0.7)0.53
Pneumococcal bacteraemia1 (2)01 (1.6)002 (0.7)0.21
Pyomyositis1 (2)01 (1.6)002 (0.7)0.21
Brain abscess1 (2)001 (0.3)0.03
Deep surgical site infection001 (1.6)001 (0.3)0.65
Epididymitis01 (1.9)0001 (0.3)0.65
Gram negative bacteraemia01 (1.9)0001 (0.3)0.65
Lung abscess01 (1.9)0001 (0.3)0.65
Mastoiditis001 (1.6)001 (0.3)0.65
Retropharyngeal abscess001 (1.6)001 (0.3)0.65
Superficial surgical site infection01 (1.9)0001 (0.3)0.65
Total50526310034299 (100)NA
  • *The p value is for pre-implementation compared with combined postimplementation data (PDSA1-Post-PDSA).

  • †Complicated appendicitis is defined as presence of perforation, peritonitis or pus in the peritoneum.

  • NA, not available; PDSA, Plan-Do-Study-Act.