Table 4

Confidence in synthesised findings using the GRADE-CERQual framework

Summary of review findingStudies contributing to the findingMethodological limitationsCoherenceAdequacyRelevanceCERQual confidence assessmentExplanation of the CERQual evidence
Information packaging (using quantifiable evidence of patient deterioration) affected perceived communication credibility15 33–39Low concerns regarding study methodologyLow concerns about coherenceLow concerns about adequacyLow concerns about relevanceHigh ConfidenceAll studies, demonstrated good methodology, data were considered moderately thick with high numbers of participants and methods, a high no of studies contributed to review finding,
Flattened hierarchy and were organisational components affecting escalation of care15 31 32 34 35 41–46Low concerns regarding methodologyLow concerns about coherenceLow concerns about adequacyLow concerns about relevanceHigh ConfidenceOne study with minor concerns regarding methodology (survey), high no of studies contributing to finding, data were considered moderately thick with high numbers of participants and methods
Workload and staffing were factors considered by clinical staff to affect their Situational awareness of patient deterioration.15 32 34–36 41 42 45 47–52Minor concerns regarding methodologyLow concerns about coherenceLow concerns about adequacyLow concerns about relevanceHigh confidenceTwo studies with minor methodological concerns with one study where using a survey, and another study using participants for a focus group put forward by head nurse, high no of studies contributing to review finding, rich data sources and multiple methods of data collection, data were considered moderately thick with high numbers of participants and methods
Team functioning caused problems or facilitated care during escalation15 32 33 35 36 41–45 47–51Minor concerns regarding methodologyLow concerns about coherenceLow concerns about adequacyLow concerns about relevanceHigh confidenceTwo studies with methodological concerns, one study where using a survey, and another study using participants for a focus group put forward by head nurse, all other studies demonstrate good methodology, high no of studies contributing to review finding, data were considered moderately thick with high numbers of participants and methods
Soft signal of patient deterioration used by clinical staff indicating a patient’s worsening condition, not adequately represented in Early Warning Score15 31 33 35 36 38 41 42 44 46 49–51 54–56Moderate concerns regarding methodologyLow concerns about coherenceModerate concerns about adequacyLow concerns about relevanceModerate ConfidenceThree studies had methodological concerns. One utilising a survey methodology with open ended-questions, the other was being observed by the implementer of the local Medical Emergency Team (MET), the last one using participants for a focus group put forward by head nurse, large no of studies contributing to synthesis finding,
Clinician confidence affected decision making during escalation of care31–36 38 43–45 47 49–52 55Moderate concerns about methodologyLow concerns about coherenceModerate concerns about adequacyLow concerns about relevanceModerate confidenceFour studies had methodological concerns, two studies utilised a survey methodology with open ended-questions, the other study had a focus group where participants were selected by head nurse, the other had observation completed by the implementer of the local RRT, data were considered moderately thick with high numbers of participants and different methods, large no of studies contributing to synthesis finding
Clinical Assessment skills relating to patient assessment and staff experience positively or negatively affected deterioration detection by clinical staff15 35 36 38 42 43 46 49–51 54 55Moderate concerns regarding methodologyLow concerns about coherenceModerate concerns about adequacyLow concerns about relevanceModerate ConfidenceTwo studies with methodological concerns. One had observations completed by the implementer of the local RRT, the other study had a focus group where participants were selected by head nurse, data were considered moderately thick
  • GRADE, Grading of Recommendations Assessment, Development and Evaluation; RRT, rapid response ream.