Table 2

Performance on key hospital-wide process measures during the initiative to reduce HAI and sepsis mortality

Process measure	2013	2014	2015	2016	2017	Estimate*	95% CI	P value
Urinary catheter utilization ratio†	0.11	0.14	0.12	0.12	0.12	0.001	−0.003 to 0.005	0.63
Number of urine cultures performed per 1000 patient-days	59	113	98	105	100	0.080	0.075 to 0.084	<0.0001
Adherence to urinary catheter maintenance bundle (%)	n/m	n/m	61	93	97
Central venous catheter utilization ratio†	0.15	0.18	0.21	0.21	0.18	0.045	0.042 to 0.048	<0.0001
Number of blood cultures performed per 1000 patient-days	84	174	174	177	174	0.118	0.115 to 0.121	<0.0001
Adherence to central line maintenance bundle (%)	n/m	n/m	90	99	99
Correct timing of perioperative antibiotics (%)	n/m	n/m	n/m	99	99
Patients who received chlorhexidine wipes night before surgery (%)	n/m	n/m	n/m	80	n/m
Patients who received chlorhexidine wipes morning of surgery (%)	n/m	n/m	n/m	95	n/m
Adherence to sepsis 3-hour bundle (%)	20	34	31	37	35	0.095	0.071 to 0.120	<0.0001
Adherence to sepsis 6-hour bundle (%)	4	10	7	n/m	n/m
Adherence to overall sepsis bundle (%)	14	26	25	32	34	0.166	0.139 to 0.194	<0.0001

*Estimate=Poisson regression estimate for reduction over 5 years.
†Utilization ratio=number of catheter-days divided by number of patient-days of care.
HAI, healthcare-associated infection; n/m, not measured.