Model | Variable | OR (95% CI) | P value |
Medication-related problems | |||
1 | Gender (female) | 0.51 (0.11 to 2.34) | 0.38 |
2 | Age | 1.00 (0.93 to 1.08) | 0.91 |
3 | ICU LOS | 1.01 (0.96 to 1.07) | 0.79 |
4 | APACHE II | 1.01 (0.92 to 1.12) | 0.8 |
5 | Number of home medications (pre-ICU) | 1.22 (0.99 to 1.57) | 0.08 |
6 | RRT | 2.042 (0.42 to 15.0) | 0.41 |
7 | CVS | 3.90 (0.81 to 28.44) | 0.12 |
8 | Number of medications on discharge from ICU | 1.25 (0.95 to 1.72) | 0.13 |
9 | Number of analgesic medications on discharge from ICU | 1.47 (0.75 to 3.77) | 0.34 |
Significant medication-related problems (severity ≥3) | |||
1 | Gender (female) | 0.59 (0.16 to 2.02) | 0.40 |
2 | Age | 1.00 (0.95 to 1.06) | 0.92 |
3 | ICU LOS | 0.99 (0.95 to 1.03) | 0.54 |
4 | APACHE II | 1.04 (0.97 to 1.14) | 0.30 |
5 | Number of home medications (pre-ICU) | 1.09 (0.94 to 1.27) | 0.26 |
6 | RRT | 1.56 (0.47 to 5.42) | 0.47 |
7 | CVS | 1.53 (0.48 to 4.93) | 0.47 |
8 | Number of medications on discharge from ICU | 1.16 (0.94 to 1.45) | 0.17 |
9 | Number of analgesic medications on discharge from ICU | 2.02 (1.14 to 4.26) | 0.03 |
APACHE II, Acute Physiology and Chronic Health Evaluation II; CVS, cardiovascular support (use of vasopressor therapy in the ICU); ICU LOS, intensive care unit length of stay; RRT, renal replacement therapy; SIMD, Scottish Index of Multiple Deprivation.