CABG n=340 | CABG+valve n=85 | Valve n=489 | Other surgical procedures n=58 | |||||
Cont n=193 | Intv n=147 | Cont n=49 | Intv n=36 | Cont n=230 | Intv n=259 | Cont n=34 | Intv n=24 | |
Prescribed antibiotic on fifth postoperative day (95% CI) | 33/17.1% (12.1 to 23.2) | 16/10.4% (6.4 to 17.1) | 9/18.4% (8.8 to 32.0) | 3/8.3% (1.8 to 22.5) | 17/7.4% (4.4 to 11.6) | 11/4.2% (2 .5 to 7.5) | 5/14.7% (5.0 to 31.1) | 0/0% (0.0 to 14.2) |
Airway infection (95% CI) | 14/4.7% (2.2 to 8.1) | 2/1.4% (0.2 to 4.8) | 2/4.1% (0.5 to 14.0) | 1/2.8% (0.1 to 14.5) | 8/3.5% (1.5 to 6.7) | 7/2.7% (1.1 to 5.5) | 0/0% (0 to 10.3) | 0/0% (0.0 to 14.2) |
Superficial surgical site infection (95% CI) | 13/6.7% (3.6 to 11.2) | 9/7.5% (3.8 to 13.0) | 1/2.0% (0.1 to 10.9) | 1/2.8% (0.1 to 14.5) | 4/1.5% (0.5 to 4.4) | 4/1.5% (0.4 to 3.9) | 1/2.9% (0.1 to 15.3) | 0/0% (0.0 to 14.2) |
Deep surgical site infection (95% CI) | 5/2.6% (0.8 to 5.9) | 2/1.6% (0.2 to 5.5) | 1/2.0% (0.1 to 10.9) | 0/0% (0.0 to 9.7) | 0/0% (0.0 to 1.6) | 0/0% (0.0 to 1.4) | 0/0% (0.0 to 10.3) | 0/0% (0.0 to 14.2) |
Urinary tract infection (95% CI) | 1/0.5% (0.0 to 2.9) | 0/0% (0.0 to 2.5) | 1/2.0% (0.1 to 10.9) | 1/2.8% (0.1 to 14.5) | 0/0% (0.0 to 1.6) | 0/0% (0.0 to 1.4) | 0/0% (0.0 to 10.3) | 0/0% (0.0 to 14.2) |
Other infections (95% CI) | 0/2.1% (0.6 to 5.2) | 3/2.0% (0.4 to 5.8) | 4/8.2% (2.3 to 19.6) | 0/0% (0.0 to 9.7) | 5/2.2% (0.7 to 5.0) | 0/0% (0.0 to 1.4) | 4/0% (0.0 to 10.3) | 1/4.2% (0.1 to 21.1) |
Other infections: endocarditis, pericarditis, chronic infection in the hip, no specific focus for infection, increase in infection parameters.
CABG, coronary artery bypass graft; Cont, control group; Intv, intervention group (measured as intention to treat).