Table 3

Reasons for prescribing antibiotics distributed by type of surgery

CABG
n=340
CABG+valve
n=85
Valve
n=489
Other surgical procedures
n=58
Cont
n=193
Intv
n=147
Cont
n=49
Intv
n=36
Cont
n=230
Intv
n=259
Cont
n=34
Intv
n=24
Prescribed antibiotic on fifth postoperative day (95% CI)33/17.1%
(12.1 to 23.2)
16/10.4%
(6.4 to 17.1)
9/18.4%
(8.8 to 32.0)
3/8.3%
(1.8 to 22.5)
17/7.4%
(4.4 to 11.6)
11/4.2%
(2 .5 to 7.5)
5/14.7%
(5.0 to 31.1)
0/0%
(0.0 to 14.2)
Airway infection  (95% CI)14/4.7%
(2.2 to 8.1)
2/1.4%
(0.2 to 4.8)
2/4.1%
(0.5 to 14.0)
1/2.8%
(0.1 to 14.5)
8/3.5%
(1.5 to 6.7)
7/2.7%
(1.1 to 5.5)
0/0%
(0 to 10.3)
0/0%
(0.0 to 14.2)
Superficial surgical site infection  (95% CI)13/6.7%
(3.6 to 11.2)
9/7.5%
(3.8 to 13.0)
1/2.0%
(0.1 to 10.9)
1/2.8%
(0.1 to 14.5)
4/1.5%
(0.5 to 4.4)
4/1.5%
(0.4 to 3.9)
1/2.9%
(0.1 to 15.3)
0/0%
(0.0 to 14.2)
Deep surgical site infection (95% CI)5/2.6%
(0.8 to 5.9)
2/1.6%
(0.2 to 5.5)
1/2.0%
(0.1 to 10.9)
0/0%
(0.0 to 9.7)
0/0%
(0.0 to 1.6)
0/0%
(0.0 to 1.4)
0/0%
(0.0 to 10.3)
0/0%
(0.0 to 14.2)
Urinary tract infection (95% CI)1/0.5%
(0.0 to 2.9)
0/0%
(0.0 to 2.5)
1/2.0%
(0.1 to 10.9)
1/2.8%
(0.1 to 14.5)
0/0%
(0.0 to 1.6)
0/0%
(0.0 to 1.4)
0/0%
(0.0 to 10.3)
0/0%
(0.0 to 14.2)
Other infections (95% CI)0/2.1%
(0.6 to 5.2)
3/2.0%
(0.4 to 5.8)
4/8.2%
(2.3 to 19.6)
0/0%
(0.0 to 9.7)
5/2.2%
(0.7 to 5.0)
0/0%
(0.0 to 1.4)
4/0%
(0.0 to 10.3)
1/4.2%
(0.1 to 21.1)
  • Other infections: endocarditis, pericarditis, chronic infection in the hip, no specific focus for infection, increase in infection parameters.

  • CABG, coronary artery bypass graft; Cont, control group; Intv, intervention group (measured as intention to treat).