Comparison of AUROC, sensitivity and specificity for the MLA applied to Sepsis-3 and severe sepsis detection, and the SIRS criteria, MEWS score, qSOFA and SOFA scores for severe sepsis detection
| MLA (sepsis-3) | MLA (severe sepsis) | SIRS | MEWS | qSOFA | SOFA | |
| AUROC | 0.91 (0.90 to 0.92) | 0.96 (0.95 to 0.97) | 0.76 | 0.55 | 0.55 | 0.77 |
| Sensitivity | 0.83 (0.81 to 0.86) | 0.90 (0.88 to 0.91) | 0.64 | 0.42 | 0.13 | 0.67 |
| Specificity | 0.96 (0.95 to 0.98) | 0.85 (0.82 to 0.87) | 0.88 | 0.64 | 0.97 | 0.83 |
All were applied to the retrospective analysis of CRMC patient data (n=1665). Data in parentheses corresponds to a 95% CI.
AUROC, area under the ROC curve; CRMC, Cape Regional Medical Center; MEWS, Modified Early Warning Score; MLA, machine learning algodiagnostic; qSOFA, quick SOFA; ROC, receiver operator characteristic; SIRS, systemic inflammatory response syndrome; SOFA, Sequential (Sepsis-Related) Organ Failure Assessment.