RT Journal Article SR Electronic T1 Effect of interventions to improve safety culture on healthcare workers in hospital settings: a systematic review of the international literature JF BMJ Open Quality JO BMJ Open Qual FD British Medical Journal Publishing Group SP e002506 DO 10.1136/bmjoq-2023-002506 VO 13 IS 2 A1 Finn, Mairead A1 Walsh, Aisling A1 Rafter, Natasha A1 Mellon, Lisa A1 Chong, Hui Yi A1 Naji, Abdullah A1 O'Brien, Niall A1 Williams, David J A1 McCarthy, Siobhan Eithne YR 2024 UL http://bmjopenquality.bmj.com/content/13/2/e002506.abstract AB Background In an era of safety systems, hospital interventions to build a culture of safety deliver organisational learning methodologies for staff. Their benefits to hospital staff are unknown. We examined the literature for evidence of staff outcomes. Research questions were: (1) how is safety culture defined in studies with interventions that aim to enhance it?; (2) what effects do interventions to improve safety culture have on hospital staff?; (3) what intervention features explain these effects? and (4) what staff outcomes and experiences are identified?Methods and analysis We conducted a mixed-methods systematic review of published literature using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search was conducted in MEDLINE, EMBASE, CINAHL, Health Business Elite and Scopus. We adopted a convergent approach to synthesis and integration. Identified intervention and staff outcomes were categorised thematically and combined with available data on measures and effects.Results We identified 42 articles for inclusion. Safety culture outcomes were most prominent under the themes of leadership and teamwork. Specific benefits for staff included increased stress recognition and job satisfaction, reduced emotional exhaustion, burnout and turnover, and improvements to working conditions. Effects were documented for interventions with longer time scales, strong institutional support and comprehensive theory-informed designs situated within specific units.Discussion This review contributes to international evidence on how interventions to improve safety culture may benefit hospital staff and how they can be designed and implemented. A focus on staff outcomes includes staff perceptions and behaviours as part of a safety culture and staff experiences resulting from a safety culture. The results generated by a small number of articles varied in quality and effect, and the review focused only on hospital staff. There is merit in using the concept of safety culture as a lens to understand staff experience in a complex healthcare system.Data are available upon reasonable request.