Fat embolism syndrome (FES) due to extensive bone marrow necrosis (BMN) in sickle cell
disease (SCD) is a potentially under-diagnosed complication associated with severe …

Abstract Background Deoxygenated sickle hemoglobin (HbS) polymerization drives the
pathophysiology of sickle cell disease. Therefore, direct inhibition of HbS polymerization has …

We report here the clinicopathological features, management and outcomes of the first 10
patients (eight men and two women) with SCD and COVID-19 infection treated in our …

Fat embolism syndrome is a devastating complication of sickle cell disease resulting from
extensive bone marrow necrosis and associated with high mortality rates, while survivors …

Diagnosis of invasive aspergillosis (IA) remains a challenge as the clinical manifestations
are not specific, and a histological diagnosis is often unfeasible. The 2002 European …

Aim Hospital autopsy rates have been falling steadily over recent decades. One factor that
has been implicated in this decline is the perception that the general public views …

CD160 is a human natural killer (NK)-cell–activating receptor that is also expressed on T-
cell subsets. In the present study, we examined 811 consecutive cases of B-cell …

Background Posttransfusion hyperhemolysis syndrome is a rare but life‐threatening form of
delayed hemolytic transfusion reaction with lysis of both transfused and autologous red …

Abstract Treatment of post-transfusion hyperhaemolysis syndrome in Sickle Cell Disease
with the anti-IL6R humanised monoclonal antibody Tocilizumab It is characterised by brisk …

The article discusses a 2019 study on fat embolism syndrome (FES) in sickle cell disease
(SCD) and its diagnosis and emergency therapies. Topics covered include the findings of …