Advances in using MRI probes and sensors for in vivo cell tracking as applied to regenerative medicine
AK Srivastava, DK Kadayakkara… - Disease models & …, 2015 - journals.biologists.com
The field of molecular and cellular imaging allows molecules and cells to be visualized in
vivo non-invasively. It has uses not only as a research tool but in clinical settings as well, for …
vivo non-invasively. It has uses not only as a research tool but in clinical settings as well, for …
Preclinical evidence that PD1 blockade cooperates with cancer vaccine TEGVAX to elicit regression of established tumors
Biomarker studies have shown that expression of the T-cell coregulatory ligand PDL1 on
tumor cells correlates with clinical responsiveness to the PD1 antibody nivolumab. Here, we …
tumor cells correlates with clinical responsiveness to the PD1 antibody nivolumab. Here, we …
Inflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis
DK Kadayakkara, PL Beatty, MS Turner, JM Janjic… - Pancreas, 2010 - journals.lww.com
Objective: Pancreatitis occurs as an extraintestinal complication of inflammatory bowel
disease (IBD), but the cause is poorly understood. Mucin 1 (MUC1) is overexpressed in an …
disease (IBD), but the cause is poorly understood. Mucin 1 (MUC1) is overexpressed in an …
[HTML][HTML] Assaying macrophage activity in a murine model of inflammatory bowel disease using fluorine-19 MRI
DK Kadayakkara, S Ranganathan, WB Young… - Laboratory …, 2012 - nature.com
Macrophages have an important role in the pathogenesis of most chronic inflammatory
diseases. A means of non-invasively quantifying macrophage migration would contribute …
diseases. A means of non-invasively quantifying macrophage migration would contribute …
[HTML][HTML] Label-free in vivo molecular imaging of underglycosylated mucin-1 expression in tumour cells
Alterations in mucin expression and glycosylation are associated with cancer development.
Underglycosylated mucin-1 (uMUC1) is overexpressed in most malignant adenocarcinomas …
Underglycosylated mucin-1 (uMUC1) is overexpressed in most malignant adenocarcinomas …
19F spin–lattice relaxation of perfluoropolyethers: dependence on temperature and magnetic field strength (7.0–14.1 T)
Fluorine (19 F) MRI of perfluorocarbon-labeled cells has become a powerful technique to
track the migration and accumulation of cells in living organisms. It is common to label cells …
track the migration and accumulation of cells in living organisms. It is common to label cells …
Fluorine-19 labeling of stromal vascular fraction cells for clinical imaging applications
LC Rose, DK Kadayakkara, G Wang… - Stem cells …, 2015 - academic.oup.com
Stromal vascular fraction (SVF) cells are used clinically for various therapeutic targets. The
location and persistence of engrafted SVF cells are important parameters for determining …
location and persistence of engrafted SVF cells are important parameters for determining …
In Vivo 19F MR Imaging Cell Tracking of Inflammatory Macrophages and Site-specific Development of Colitis-associated Dysplasia
Purpose To investigate whether the magnitude of in vivo fluorine 19 (19F) magnetic
resonance (MR) imaging signal is associated with subsequent development of colitis …
resonance (MR) imaging signal is associated with subsequent development of colitis …
[HTML][HTML] Herpes simplex virus-2 esophagitis in a young immunocompetent adult
DK Kadayakkara, A Candelaria, YE Kwak… - Case Reports in …, 2016 - hindawi.com
Herpes simplex esophagitis (HSE) is commonly identified in immunosuppressed patients. It
is rare among immunocompetent patients and almost all of the reported cases are due to …
is rare among immunocompetent patients and almost all of the reported cases are due to …
Paradoxical decrease in the capture and lymph node delivery of cancer vaccine antigen induced by a TLR4 agonist as visualized by dual-mode imaging
Traditionally, cell-mediated immune responses to vaccination in animal models are
evaluated by invasive techniques such as biopsy and organ extraction. We show here that …
evaluated by invasive techniques such as biopsy and organ extraction. We show here that …